Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity linked to bortezomib, a proteasome inhibitor used in the therapy of a number of myeloma. Its synthesis or analyze is very important for making sure the purity and security on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor from the synthesis of abiraterone acetate, a drug Employed in the procedure of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular types of most cancers, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is very important for optimizing the output method and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and these intermediates PMD are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the remedy of breast most cancers. Many intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug powerful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and smaller mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, 3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester that have several apps, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for form 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that are Employed in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication utilized to manage type two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).